Category: Behind the Science
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Expanding Frontiers in Neuroimmunology
Jon Brotchie reports back with highlights from the recent Neuroimmunology Drug Development Summit in Boston, in particular how TREM2 is emerging as one of the most promising new targets for Parkinson’s, both in terms of mechanism and the variety of approaches we have to potentially manipulate it.
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How AI could help dramatically change the drug discovery process
The upside of integrating AI into the drug discovery process is potentially game-changing, though it’s also important to be clear-eyed and not get too caught up in the hype. Jon Brotchie reflects on AI’s potential benefits in drug development for Parkinson’s, from finding new and better molecules for novel un-imagined targets, and the repurposing of…
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Parkinson’s disease prevalence is soaring—but is there a good news story hidden in the data?
As Parkinson’s becomes the fastest-growing neurological disorder worldwide, its rising prevalence raises urgent questions about public health and economic impact. Could improved diagnosis, treatment, and life expectancy offer a hidden silver lining within the statistics?
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Highlights from Neuroscience 2024
At the annual summit of the Society for Neuroscience in Chicago, it was clearer than ever that collaboration and advancing technologies are central to moving the field forward.
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New frontiers in inflammasome therapeutics
Insights from Atuka’s recent visit to the 6th Annual Inflammasome Summit in Boston.
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What the market overlooked in Seelos’s recent trehalose study
Atuka’s Jonathan Brotchie and Patrick Howson take a deeper look at the top-line results for IV trehalose, an ALS treatment, and see signs of potential for the compound that the market may have missed.
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Tavapodon offers great promise as a new therapeutic for Parkinson’s disease
On the encouraging topline results from Cerevel Therapeutics’ Phase III TEMPO-3 trial for tavapadon, a D1/D5 dopamine receptor partial agonist.