
Collaboration beyond the lab
Collaboration isn’t just an outcome of Atuka’s work, it is the work. Unlike traditional CROs, we go shoulder-to-shoulder with our partners, from idea generation and study design, to grant writing and formal presentations, helping them acquire the funding and support needed to advance new life-altering therapeutics.
WHITE PAPER

Optimizing Preclinical Studies for Parkinson’s Disease Therapeutics
Strategies to optimize preclinical study design for therapeutic development and reduce translational risk.
Collaboration is one of the three core pillars that guide Atuka as an organization. It’s embedded in the way we work internally among our teams, but it also defines how we work externally, with our partners, stakeholders, and the broader Parkinson’s community. That includes doing more to include patients and their priorities in the entire drug discovery and development process.
Atuka’s commitment to collaboration is not aspirational; it’s demonstrable. Our collaborators aren’t just receiving a report, they’re gaining a thinking partner—one fully invested in their pursuit of novel therapeutics that will improve the lives of patients.
One of the most obvious examples of our commitment to collaboration is the work we perform to help our partners secure grant funding. We have a long history of working with The Michael J. Fox Foundation for Parkinson’s Research, as well as other funding organizations, in obtaining grants to develop new models of the disease. That often means directly assisting our partners in designing their proposed studies and crafting their applications—from providing expert advice on preclinical development packages and model selection based on the therapeutic mechanism of action, to guiding partners through the entire submission process.
• Over 150 grant applications supported
• Over $50 million in non-dilutive funding secured
We work with our partners on these funding proposals at no cost, seeing it as a key component of our external collaborations and one of the more impactful ways we can contribute to advances in the broader research community. For our partners, securing such grants often increases their chances of obtaining non-dilutive funding, while helping to generate robust datasets on which future development decisions can be made.
A track record of collaborative impact:
Over 150 grant applications supported
We have actively contributed to the development, editing, and scientific refinement of more than 150 grant applications, whether as co-applicant, named collaborator, or strategic consultant. Notable funding bodies include:
• Michael J. Fox Foundation
• Department of Defense (USA)
• Canadian Institutes of Health Research (CIHR)
• Ontario Research Fund
• Brain Canada
• NIH (National Institutes of Health)
• Weston Family Foundation
• Cure Parkinson’s Trust
Over $50 million in non-dilutive funding secured
Our collaborative grant work has helped secure over $50 million in non-dilutive funding for our partners and Atuka-led projects. Highlights include:
• USD 1.5M from MJFF for Kannalife’s KLS-13019 PD therapeutic
• CAD 1.5M from Weston Family Foundation to support UHN’s work on trehalose
• CAD 4.4M from Ontario Research Fund for development of next-generation animal models of PD (Atuka contributed matching funds)
• CAD 2.4M from Brain Canada for a zebrafish drug screening platform (Atuka provided matched funding)
REPEAT ENGAGEMENT AND A diverse NETWORK OF partneRS
We’ve been co-applicants on at least 14 successful Michael J. Fox Foundation grants and named collaborators on many more. In several cases, we have worked with partners across multiple submission rounds—revising applications to address reviewer concerns and secure eventual funding.
This is just one of the ways in which Atuka is different from traditional CROs, with successful collaborations across a broad range of partner organizations, including:
• Small biotechs (Kannalife, Yumanity)
• Academic institutions (Yale, Harvard, MIT, UCSF, UHN)
• Major pharmaceutical companies (AZ, Pfizer, Merck)
• Advocacy groups and patient foundations (MJFF, CPT)
• Independent researchers and early-stage startups (Sea Pharma)
Of course, not all grant submissions are initially successful. In many cases we have helped our partners refine subsequent versions of their proposals to overcome reviewers’ objections. And our assistance can extend beyond the proposals themselves; as many granting programs require matching industry funding, Atuka has, on several occasions, provided the additional support necessary to secure the grant.
Whether you’re an academic researcher, leader in pharma or biotech, VC funder, or patient advocate, if you’re interested in developing a therapy for Parkinson’s please reach out to us. Even if it’s only an exploratory conversation, this is where true collaboration begins.
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