Non-human primate
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Anxiety assessment using the Human Intruder Test (HIT)
Assessment of anxiety-like behaviours in the macaque Anxiety is a complex psychological state in which typically harmless environmental stimuli provoke negative emotional expectations. In humans, anxiety disorders are multifaceted, arising…
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Biodistribution in rodent and non-human primate
The biodistribution services that Atuka offers include evaluation of the distribution of viral vectors, small molecules, antibodies and other biologics, PET tracers, cells, exosomes and antisense oligonucleotides. Additional Test Items…
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Non-human primate model of dyskinesia
Available for use in both new (marmoset) and old-world (macaque) primates, MPTP induces degeneration of dopaminergic neurons in the substantia nigra which translates to a behavioural impairment similar to that…
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MPTP-lesioned non-human primate
Systemic administration of MPTP to non-human primates produces a behavioural phenotype that recapitulates the motor symptoms of Parkinson’s disease. MPTP induces a robust and stable parkinsonian syndrome that includes bradykinesia…
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